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1

Identification of a γc Receptor Antagonist that Prevents Reprogramming of Human Tissue-resident Cytotoxic T Cells by IL15 and IL21

Ciszewski, Cezary, Discepolo, Valentina, Pacis, Alain, Doerr, Nick, Tastet, Olivier, Mayassi, Toufic, Maglio, Mariantonia, Basheer, Asjad, Al-Mawsawi, Laith Q., Green, Peter, Auricchio, Renata, Tronco

Journal:

Gastroenterology

Year:

2019

Language:

english

File:

PDF, 20.56 MB

english, 2019

2

ChemInform Abstract: Allosteric Inhibitor Development Targeting HIV-1 Integrase

Laith Q. Al-Mawsawi, Nouri Neamati

Journal:

Year:

2011

File:

PDF, 18 KB

2011

3

Allosteric Inhibitor Development Targeting HIV-1 Integrase

Laith Q. Al-Mawsawi, Nouri Neamati

Journal:

Year:

2011

Language:

english

File:

PDF, 1.10 MB

english, 2011

4

HIV-1 integrase inhibitors: 2005–2006 update

Raveendra Dayam, Rambabu Gundla, Laith Q. Al-Mawsawi, Nouri Neamati

Journal:

Medicinal Research Reviews

Year:

2008

Language:

english

File:

PDF, 813 KB

english, 2008

5

Discovery of structurally diverse HIV-1 integrase inhibitors based on a chalcone pharmacophore

Jinxia Deng, Tino Sanchez, Laith Q. Al-Mawsawi, Raveendra Dayam, Rosendo A. Yunes, Antonio Garofalo, Michael B. Bolger, Nouri Neamati

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 864 KB

english, 2007

6

Substituted 2-pyrrolinone inhibitors of HIV-1 integrase

Raveendra Dayam, Laith Q. Al-Mawsawi, Nouri Neamati

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 215 KB

english, 2007

7

Discovery of novel non-cytotoxic salicylhydrazide containing HIV-1 integrase inhibitors

Laith Q. Al-Mawsawi, Raveendra Dayam, Laleh Taheri, Myriam Witvrouw, Zeger Debyser, Nouri Neamati

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 125 KB

english, 2007

8

From Ligand to Complexes: Inhibition of Human Immunodeficiency Virus Type 1 Integrase by β-Diketo Acid Metal Complexes

Sechi, Mario, Bacchi, Alessia, Carcelli, Mauro, Compari, Carlotta, Duce, Elenia, Fisicaro, Emilia, Rogolino, Dominga, Gates, Paul, Derudas, Marco, Al-Mawsawi, Laith Q.

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 517 KB

english, 2006

9

Inhibitory profile of a LEDGF/p75 peptide against HIV-1 integrase: Insight into integrase–DNA complex formation and catalysis

Laith Q. Al-Mawsawi, Frauke Christ, Raveendra Dayam, Zeger Debyser, Nouri Neamati

Journal:

Year:

2008

Language:

english

File:

PDF, 337 KB

english, 2008

10

Four-tiered π interaction at the dimeric interface of HIV-1 integrase critical for DNA integration and viral infectivity

Laith Q. Al-Mawsawi, Anneleen Hombrouck, Raveendra Dayam, Zeger Debyser, Nouri Neamati

Journal:

Year:

2008

Language:

english

File:

PDF, 1.06 MB

english, 2008

11

Blocking interactions between HIV-1 integrase and cellular cofactors: an emerging anti-retroviral strategy

Laith Q. Al-Mawsawi, Nouri Neamati

Journal:

Trends in Pharmacological Sciences

Year:

2007

Language:

english

File:

PDF, 962 KB

english, 2007

12

Quinolone 3-Carboxylic Acid Pharmacophore: Design of Second Generation HIV-1 Integrase Inhibitors

Dayam, Raveendra, Al-Mawsawi, Laith Q., Zawahir, Zahrah, Witvrouw, Myriam, Debyser, Zeger, Neamati, Nouri

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 1.33 MB

english, 2008

13

Single amino acid substitution in HIV-1 integrase catalytic core causes a dramatic shift in inhibitor selectivity

Laith Q. Al-Mawsawi, Mario Sechi, Nouri Neamati

Journal:

Year:

2007

Language:

english

File:

PDF, 247 KB

english, 2007

14

Single-Round, Multiplexed Antibody Mimetic Design through mRNA Display

Olson, C. Anders, Nie, Jeff, Diep, Jonathan, Al-Shyoukh, Ibrahim, Takahashi, Terry T., Al-Mawsawi, Laith Q., Bolin, Jennifer M., Elwell, Angela L., Swanson, Scott, Stewart, Ron, Thomson, James A., Soh

Journal:

Angewandte Chemie

Year:

2012

Language:

english

File:

PDF, 1.08 MB

english, 2012

15

Single-Round, Multiplexed Antibody Mimetic Design through mRNA Display

Olson, C. Anders, Nie, Jeff, Diep, Jonathan, Al-Shyoukh, Ibrahim, Takahashi, Terry T., Al-Mawsawi, Laith Q., Bolin, Jennifer M., Elwell, Angela L., Swanson, Scott, Stewart, Ron, Thomson, James A., Soh

Journal:

Angewandte Chemie International Edition

Year:

2012

Language:

english

File:

PDF, 1.10 MB

english, 2012

16

Arrangement of Core Membrane Segments in the MotA/MotB Proton-Channel Complex of Escherichia coli †

Braun, Timothy F., Al-Mawsawi, Laith Q., Kojima, Seiji, Blair, David F.

Journal:

Year:

2004

Language:

english

File:

PDF, 358 KB

english, 2004

17

Anti-infectives Clinical progress of HIV-1 integrase inhibitors

Al-Mawsawi, Laith Q, Al-Safi, Rasha I, Neamati, Nouri

Journal:

Expert Opinion on Emerging Drugs

Year:

2008

Language:

english

File:

PDF, 233 KB

english, 2008

18

HIV-1 Integrase Inhibitors

Raveendra Dayam,Laith Q. Al-Mawsawi,Dr Nouri Neamati

Journal:

Year:

2007

Language:

english

File:

PDF, 927 KB

english, 2007

19

Short Communication: HIV-1 Gag Genetic Variation in a Single Acutely Infected Participant Defined by High-Resolution Deep Sequencing

Al-Mawsawi, Laith Q., Wu, Nicholas C., De La Cruz, Justin, Shi, Vivian Cai, Wu, Ting-Ting, Daar, Eric S., Lewis, Martha J., Yang, Otto O., Sun, Ren

Journal:

AIDS Research and Human Retroviruses

Year:

2014

Language:

english

File:

PDF, 521 KB

english, 2014

20

Recent advances in the design and discovery of small-molecule therapeutics targeting HER2/neu

Dayam, Raveendra, Grande, Fedora, Al-Mawsawi, Laith Q, Neamati, Nouri

Journal:

Expert Opinion on Therapeutic Patents

Year:

2007

Language:

english

File:

PDF, 554 KB

english, 2007

21

High-throughput profiling of point mutations across the HIV-1 genome

Al-Mawsawi, Laith Q, Wu, Nicholas C, Olson, C, Shi, Vivian, Qi, Hangfei, Zheng, Xiaojuan, Wu, Ting-Ting, Sun, Ren

Journal:

Year:

2014

Language:

english

File:

PDF, 2.12 MB

english, 2014

22

Design of Second Generation HIV-1 Integrase Inhibitors

Deng, Jinxia, Dayam, Raveendra, Al-Mawsawi, Laith, Neamati, Nouri

Journal:

Current Pharmaceutical Design

Year:

2007

Language:

english

File:

PDF, 394 KB

english, 2007

23

A Quantitative High-Resolution Genetic Profile Rapidly Identifies Sequence Determinants of Hepatitis C Viral Fitness and Drug Sensitivity

Qi, Hangfei, Olson, C. Anders, Wu, Nicholas C., Ke, Ruian, Loverdo, Claude, Chu, Virginia, Truong, Shawna, Remenyi, Roland, Chen, Zugen, Du, Yushen, Su, Sheng-Yao, Al-Mawsawi, Laith Q., Wu, Ting-Ting,

Journal:

Year:

2014

Language:

english

File:

PDF, 2.67 MB

english, 2014

24

High-throughput profiling of influenza A virus hemagglutinin gene at single-nucleotide resolution

Wu, Nicholas C., Young, Arthur P., Al-Mawsawi, Laith Q., Olson, C. Anders, Feng, Jun, Qi, Hangfei, Chen, Shu-Hwa, Lu, I.-Hsuan, Lin, Chung-Yen, Chin, Robert G., Luan, Harding H., Nguyen, Nguyen, Nelso

Journal:

Scientific Reports

Year:

2014

Language:

english

File:

PDF, 4.29 MB

english, 2014

25

Functional Constraint Profiling of a Viral Protein Reveals Discordance of Evolutionary Conservation and Functionality

Wu, Nicholas C., Olson, C. Anders, Du, Yushen, Le, Shuai, Tran, Kevin, Remenyi, Roland, Gong, Danyang, Al-Mawsawi, Laith Q., Qi, Hangfei, Wu, Ting-Ting, Sun, Ren, Worobey, Michael

Journal:

Year:

2015

Language:

english

File:

PDF, 5.04 MB

english, 2015

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